Figure 4.

(A) The amino acid side chains of residues that are identical in TCL-1 and MTCP-1 are shown in red on the Cα backbone of the MTCP-1 structure (blue) looking into the β barrel in the same orientation as Fig. 2B. Electrostatic potential surface for MTCP-1 and TCL-1. The negative electrostatic potential energy surface contoured at 0.3 e/Å3 is shown in blue for the crystal structure of MTCP-1 and in red for the model of TCL-1. The black lines indicate the Cα backbone of MTCP-1 in the same view as Fig. 2A, showing the four longer strands crossing over the four shorter strands of the β barrel with the helix at the lower right side.