Figure 5.

LV area at risk quantification after ischemia/reperfusion. (a) Graphic representation of the LV infarction size measured as the percentage of infarct of total ischemic area at risk in MI + saline (control) rabbits (black bar, n = 5) and MI + EPO rabbits (white bar, n = 5). The LV area at risk was virtually identical in both groups (see Results). Data are the mean ± SEM. *P < 0.005 versus MI + saline. (b) Representative LV cross sections from a MI + saline (control) rabbit and (c) from a MI + EPO rabbit. The dark blue–stained areas are nonischemic tissue, and red-stained areas represent the ischemic LV area at risk. Infarcted areas are indicated by blanched (yellow-white) areas within this area at risk, with much less seen in the MI + EPO heart (c).