Fig. 4.

Analysis of Wnt-mediated effects on hematopoietic repopulation. (A) Raw data of short-term (6 weeks) engraftment of cultured LKSI cells. Recipients were defined as positive for engraftment if they contained >1% hematopoietic chimerism. (B) Average short-term repopulation of cultured LKSI cells. Data represent the pooled results of two independent experiments. Only recipients with >1% chimerism were included in this analysis. Error bars represent standard deviation. P values were generated by Student's t test. (C) Raw data of long-term (16 weeks) engraftment of cultured LKSI cells. Recipients were defined as positive for engraftment if they contained >1% hematopoietic chimerism. (D) Average long-term repopulation of cultured LKSI cells. Data represent the pooled results of three independent experiments. Only recipients with >1% chimerism were included in this analysis. Error bars represent standard deviation. P values were generated by Mann–Whitney nonparametric analysis.