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. Author manuscript; available in PMC: 2007 Sep 19.
Published in final edited form as: J Hepatol. 2007 Apr 5;47(2):262–269. doi: 10.1016/j.jhep.2007.03.016

Figure 6.

Figure 6

Succinate promotes activation of hepatic stellate cells. (a) Western blot for alpha-smooth muscle actin (α-SMA) in hepatic stellate cells 1, 3, and 5 days after isolation. Three-day HSC were followed either in the absence or presence of succinate (400 μM). (b) Densitometric quantification of western blots for α-SMA, normalized by GAPDH expression. Results of each of three separate experiments at each time point are shown. α-SMA expression is increased 2.3-fold in succinate-treated cells relative to untreated controls (p<0.05).