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Illustrative representation of dual splicing. (A and B) Schematic diagram of canonical splicing (A) and dual splicing (B). Boxes represent exons, and lines are introns. The dual splice site is labeled in B. (C and D) The motifs of canonical (constitutive) 5′ and 3′ splice sites (C) and of dual splice sites (D). Dotted arrows and boxes indicate the similarity of dual sites with constitutive splice sites. Uridine is shown as thymine in the logos.
