Fig. 3.

Predicting splicing outcome, using binding specificity. Each point represents a dual splice site. The x axes show the log-likelihood ratio of the binding probabilities, and the y axes show the log ratio of supporting-transcript number for the 5′ splice-site isoform relative to that of the 3′ splice-site isoform. (A) Competition at the dual splice site. The log-likelihood ratio of binding is calculated as Δb by using the high-confidence dataset. (B) Similar to A, except by using the extended set. (C) Competition by exon definition or alternative 5′/3′ splice sites. The log-likelihood ratio of binding is calculated as Δb₂ by using the extended set.