Figure 4. Clonal Igh and TCR gene rearrangements.
(A) Southern blot of HindIII digested genomic DNA hybridized to a TCRB probe. Mouse numbers are indicated, a number followed by S indicates the infiltrated tissue was spleen, L indicates the tissue was liver. C is germline control tissue. Asterisk indicates germline bands, arrows indicate clonal rearrangments. Size standards are in kb. (B) Same as in (A), except the probe was TCRD. (C and D) Same as (A) except the digest was XbaI and the probe was IGH.