Table 3.
Summary of logistic regressions
Variable | p Value for variable alone, unadjusted | p Value for variable adjusted for AED in model | p Value for AED effect adjusted for variable in model |
---|---|---|---|
Baseline, AED only | 0.005 | ||
Maternal age | 0.61 | 0.36 | 0.004 |
Maternal IQ | 0.73 | 0.46 | 0.02 |
Education (5 levels) | 0.83 | 0.65 | 0.005 |
Post–high school education (yes/no) | 0.21 | 0.14 | 0.005 |
Alcohol use (yes/no) | 0.76 | 0.68 | 0.005 |
Tobacco use (yes/no) | 0.62 | 0.45 | 0.004 |
Race(5 categories) | 0.50 | 0.54 | 0.02 |
Race (2 categories) | 0.75 | 0.78 | 0.01 |
Gestational age at enrollment | 0.32 | 0.26 | 0.002 |
Birth weight | 0.71 | 0.87 | 0.003 |
Convulsive seizures | 0.26 | 0.18 | 0.003 |
Nonconvulsiveseizures | 0.64 | 0.29 | 0.005 |
Folate (yes/no) | 0.40 | 0.59 | 0.005 |
Seizure type | 0.21 | 0.42 | 0.02 |
AED dose1st trimester | 0.004 | 0.003 | 0.004 |
AED doseentire pregnancy | 0.003 | 0.002 | 0.004 |
History of pregnancy abnormality | 0.74 | 0.80 | 0.005 |
Socioeconomic status27 | 0.56 | 0.65 | 0.01 |
AED = antiepileptic drug.