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. Author manuscript; available in PMC: 2008 Jul 4.
Published in final edited form as: Life Sci. 2007 Jun 13;81(4):306–316. doi: 10.1016/j.lfs.2007.05.021

Table 1.

The effect of sepsis on hemodynamics and the concentration of various clinical and experimental biomarkers in sham, 1-day, 3-days and 7-days post-sepsis groups. Heart rate, HR; Mean arterial pressure, MAP; rat cardiac troponin I, cTnI; C-reactive protein, CRP; endothelin-1, ET-1.

Hemodynamic charactristics and clinical parameters
Parameters Non-septic Sepsis
Sham 1-day 3-days 7-days
HR (beats/min) 355±13 457±21* 409±13* 449±7*
MAP (mmHg) 116±5 104±6 101±4 91±3*
Clinical and experimental biomarkers
cTnI (ng/ml) 2.50±0.30 5.95±1.76* 4.51±1.67* 8.34±4.39*
CRP(ng/ml) 0.15±0.04 0.61±0.06* 0.37±0.05* 0.47±0.15*
Plasma ET-1
(pg/ml)
0.84±0.05 0.79±0.08 5.67±2.07* 12.8±6.99*
Heart tissue
ET-1 (pg/g)
208±20 320±45 1037±331*# 1251±84*#
*

p<0.05 Vs. Sham

#

p<0.05 Vs. 1-day sepsis group, N=6 in each group.