Table 1.
Hemodynamic charactristics and clinical parameters | ||||
---|---|---|---|---|
Parameters | Non-septic | Sepsis | ||
Sham | 1-day | 3-days | 7-days | |
HR (beats/min) | 355±13 | 457±21* | 409±13* | 449±7* |
MAP (mmHg) | 116±5 | 104±6 | 101±4 | 91±3* |
Clinical and experimental biomarkers | ||||
cTnI (ng/ml) | 2.50±0.30 | 5.95±1.76* | 4.51±1.67* | 8.34±4.39* |
CRP(ng/ml) | 0.15±0.04 | 0.61±0.06* | 0.37±0.05* | 0.47±0.15* |
Plasma ET-1 (pg/ml) |
0.84±0.05 | 0.79±0.08 | 5.67±2.07* | 12.8±6.99* |
Heart tissue ET-1 (pg/g) |
208±20 | 320±45 | 1037±331*# | 1251±84*# |
p<0.05 Vs. Sham
p<0.05 Vs. 1-day sepsis group, N=6 in each group.