Table 2.
Summary of sepsis-induced alterations on the hemodynamic and biochemical parameters during early (1-day post-sepsis) and later (3- to 7-days post sepsis) stages. + denotes significant change compared to the sham group; ++ denotes significant change compared to the 1-day post-sepsis group.
Parameters | 1-day post sepsis | 3-7 days post sepsis |
---|---|---|
Hemodynamic | ||
HR | + | + |
MAP | No Change | No change to decrease |
+dP/dt | No change | No change |
−dP/dt | No change | Decrease |
LVEDP | + | + |
Tau | + | ++ |
Biochemical markers | ||
cTnI | + | + |
CRP | + | + |
ET-1 | No change | ++ |
Apoptosis proteins | ||
Active Caspase-3 | + | ++ |
Bax/BCl2 | + | ++ |
TRADD | + | ++ |
Release of Cyto C | No change | Increase |
Signaling proteins | ||
Phosphorylation of | ||
p38-MAPK | No change | ++ |
JNK | + | ++ |