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. Author manuscript; available in PMC: 2008 Jul 4.
Published in final edited form as: Life Sci. 2007 Jun 13;81(4):306–316. doi: 10.1016/j.lfs.2007.05.021

Table 2.

Summary of sepsis-induced alterations on the hemodynamic and biochemical parameters during early (1-day post-sepsis) and later (3- to 7-days post sepsis) stages. + denotes significant change compared to the sham group; ++ denotes significant change compared to the 1-day post-sepsis group.

Parameters 1-day post sepsis 3-7 days post sepsis
Hemodynamic
HR + +
MAP No Change No change to decrease
+dP/dt No change No change
−dP/dt No change Decrease
LVEDP + +
Tau + ++

Biochemical markers
cTnI + +
CRP + +
ET-1 No change ++

Apoptosis proteins
Active Caspase-3 + ++
Bax/BCl2 + ++
TRADD + ++
Release of Cyto C No change Increase

Signaling proteins
Phosphorylation of
 p38-MAPK No change ++
 JNK + ++