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. Author manuscript; available in PMC: 2007 Sep 19.
Published in final edited form as: Curr Neurovasc Res. 2005 Oct;2(4):271–285. doi: 10.2174/156720205774322584

Fig. (2). Nicotinamide (NIC) prevents DNA fragmentation and membrane PS externalization during anoxia.

Fig. (2)

(A), Representative pictures for DNA fragmentation and PS exposure that were determined using the TUNEL assay and annexin V labeling respectively were demonstrated in neurons 24 h following a 4 h period of anoxia. (B) Pretreatment with NIC (12.5 mM) decreased DNA fragmentation and membrane PS externalization significantly during anoxia (*p<0.01 vs. anoxia). In B, data represent the mean and SEM from 4 to 6 experimental preparations. In all cases, control = untreated neurons.