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. Author manuscript; available in PMC: 2008 Jun 1.
Published in final edited form as: Biochim Biophys Acta. 2007 Apr 20;1773(6):1007–1014. doi: 10.1016/j.bbamcr.2007.04.006

Fig. 4. Effect of anti-MUC1 antibody on trophoblast adhesion to endothelial cells.

Fig. 4

Trophoblasts were labeled with the fluorescent cell tracer CFDA-SE and added to confluent endothelial (UtMVEC) monolayers as described in Methods. Adhesion was measured after 2 h. For some experiments trophoblasts were pre-incubated with anti-MUC1 antibody or with recombinant human ICAM-1 (rICAM-1). In other experiments the endothelial cells were pre-incubated with anti-ICAM-1 or anti-E-selectin (E-sel). Adhesion is expressed as a percentage of the initial input trophoblasts and values are means ± SEMs from 3 experiments. Data were analyzed by ANOVA with Dunnett’s Multiple comparison post-test. Values marked with an asterisk were significantly different from the control (p<0.01).