Fig. 8.
Cholesterol depletion inhibits MHC class-II transfer to T cells. BLS-CD8 T cells (A and B) or Jurkat T cells (C and D) were incubated with 10 mM MCD (B and D) or in medium alone (A and C) for 10 min at room temperature. After this incubation, the T cells were co-cultured with M35-EBV cells (at 1:1 ratio) for 3 h and HLA-DR expression was analyzed by flow cytometry as described in previous figure legends.