TABLE I.
Chimerism and tumor response in patients with hematologic malignancies treated with a sibling graft
| Patient number | Disease | Maximal donor chimerism | Disease state at 8 weeks | Survival (days) |
|---|---|---|---|---|
| 1 | Lymphoma | 5% | CR | 1585* |
| 2 | Lymphoma | 10% | Died of disease | 28 |
| 6 | Myeloma | 100% | CR | 116 |
| 8 | Myeloma | 10% | Stable | 229 |
| 9 | CML | 67% | No response | 129 |
| 11 | Lymphoma | 5% | Died of disease | 29 |
| 12 | Lymphoma | 100% | CR | 222 |
| 20 | Lymphoma | 67% | Died of disease | 37 |
| 23 | CLL | 0 | PR | 179 |
| 24 | Lymphoma | 0 | Died of disease | 40 |
| 25 | AML | 100% | CR | 930* |
*
Patients currently alive and disease-free