Table 4.
Results in patients with alternative donors
| Author | n | Diagnosis | Median age (y) | Graft source | Conditioning | Chimerism (%) | Responses |
|---|---|---|---|---|---|---|---|
| Ballen [15], Umass | 7 | 1 Lymphoma
6 Solid tumor |
47 | Cord blood | 100 cGy TBI | 0 | No response |
| Colvin [30], Roger Williams | 41 | 26 Heme mal
15 Solid tumor |
58 | Mismatched relative | 100 cGy TBI | 0 | 3/6 lymphoma 7/13 AML PR/CR |
| Loren [36], UPenn | 25 | Heme malignancy | 50 | Unrelated donor | Fludara/Cytoxan/Campath | 92 | 16 PR/CR |
| Wong, MD Anderson | 29 | Heme malignancy | 59 | Unrelated donor | Fludara/Melphalan | 86 | 18/29 CR |
AML =acute myeloid leukemia; CR =complete remission; PR =partial remission; TBI =total body irradiation.