TABLE 1.
Age | Region | 5HT (ng/g tissue) | 5HT (ng/region) | 5HT turnover ratio |
---|---|---|---|---|
PN21 | cerebral cortex | 157 ± 4 | 128 ± 4 | 1.27 ± 0.09 |
hippocampus | 143 ± 5 | 13.8 ± 0.6 | 1.70 ± 0.09 | |
midbrain | 464 ± 34 | 106 ± 8 | 1.40 ± 0.09 | |
brainstem | 394 ± 14 | 47 ± 2 | 1.15 ± 0.06 | |
PN30 | cerebral cortex | 181 ± 6 | 146 ± 4 | 0.81 ± 0.08 |
striatum | 258 ± 6 | 24.0 ± 1.0 | 1.11 ± 0.04 | |
hippocampus | 164 ± 9 | 16.7 ± 1.0 | 1.30 ± 0.14 | |
midbrain | 499 ± 27 | 126 ± 6 | 0.76 ± 0.05 | |
brainstem | 394 ± 14 | 49 ± 2 | 0.74 ± 0.03 | |
PN45 | cerebral cortex | 203 ± 9 | 173 ± 9 | 0.65 ± 0.05 |
Because of the absence of sex differences for these measures, values are shown combined for males and females. For the measurements on PN21, the region designated as “cerebral cortex” includes the striatum.