Table 4.
Controls | Cases | ||||
---|---|---|---|---|---|
NAT1 genotype | N(%) | N(%) | OR | (95% CI)* | p |
NAT1*4/*4 | 386(51.3) | 463(50.3) | 1.00 | (reference) | |
NAT1*10/*10 | 42(5.6) | 68(7.4) | 1.61 | (1.04, 2.48) | 0.03 |
NAT1*4/*10 | 206(27.4) | 254(27.6) | 1.11 | (0.87, 1.40) | 0.4 |
NAT1*4/*11A or*3/*11B | 20(2.7) | 27(2.9) | 1.04 | (0.57, 1.90) | 0.9 |
NAT1*4/*3 | 31(4.1) | 26(2.8) | 0.70 | (0.40, 1.21) | 0.2 |
Other** | 67(8.9) | 83(9.0) | 1.10 | (0.77, 1.57) | 0.6 |
OR (95% CI) adjusted for age, sex, race, and study center.
Other NAT1 genotypes (<2% prevalence among controls): NAT1*10/*11A, NAT1*10/*14A, NAT1*11A/*14A, NAT1*14A/*14A, NAT1*3/*10, NAT1*3/*11A, NAT1*3/*14A, NAT1*4/*14A, NAT1*10/*14B.