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Cloning of miR-451 from immunopurified Agos from human neutrophils. (a) Sequence and secondary structure of human pre-miR-451. Mature miR-451 is shown in red. Nucleotide positions of the 3′-end of miR-451 are indicated. Percentages of clones that ended in specified nucleotide are shown in parentheses. Cloned miR-451 from human blood varied in length from 20 to 26 nt; 1% of clones were 26 nt long. (b) Genomic position of miR-451 gene in different species.
