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Metaphase spreads were prepared from MCH clones, hybridized with either chromosome-specific paint or BACs, and examined by high power fluorescence microscopy. (A) p11 probed with chromosome 2 paint; (B) p19 probed similarly; (C) p11 probed with a 2q BAC (green) and a 2p BAC (red); (D) p11 probed with a chromosome 2 BAC (red) and a chromosome 12 BAC (green).
