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. Author manuscript; available in PMC: 2008 Mar 13.
Published in final edited form as: Cancer Cell. 2007 Mar;11(3):275–289. doi: 10.1016/j.ccr.2007.01.014

Figure 8. Loss of Lzts1 enhances NMBA-induced forestomach carcinogenesis in mice.

Figure 8

A. Left Panels: Gross morphology of the forestomach and SCJ in Lzts1+/+, +/− and −/− mice (top to bottom, x 35). Middle panels: Hematoxylin and Eosin (H&E) stained forestomach sections. Normal epithelium is shown in Lzts1+/+, early infiltrating carcinoma and infiltrating carcinoma in Lzts1+/− and −/− mice. Scale bars: 100μm (A), 20μm (B and C). Right panels: retention of the remaining wild-type allele in tumor from heterozygous mice. B. Number and incidence of induced tumors in the different genotypes