Table 2.

Parameters of the NO diffusion-reaction model around an arteriole. The radius of each layer except the mast cell in the model is the distance from the center of the lumen to the outer surface of the layer.

Parameters	Values	Unit	References
Radius
RBC-rich layer	10.25	μm	text
RBC-free layer	12.5	μm	text
Endothelium layer	12.75	μm	text
Interstitial space layer	13.0	μm	text
Smooth muscle layer	16.0	μm	text
Nerve fiber layer	18.0	μm	text
Non-perfused tissue layer	100.0	μm	text
Perfused tissue layer	1000.0	μm	text
Mast cell	4.5–9	μm	[19]
Reaction rate
with Hb	1230	s−1	[6]
with O2	9.6×10−6	μM−2·s−1	[23]
with sGC	5×10−2	μM−1·s−1	[8]
Effective rate with capillary RBCs	12.4	s−1	[6]
Effective rate with oxygenated tissue	5.38×10−10	μM−1·s−1(cell/ml)−1	[24]
Density of tissue cellular sinks	1×108	cell/ml	[24]
Diffusion coefficient, NO	3300	μm2/s	[8]
Hematocrit	45%	N/A	text