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Correlation of calculated dimerization propensity and free energy of dissociation for wild-type GpA and two point mutants. Values for calc, using Eq. 4, are strongly correlated with the free energies of dissociation, ΔGdiss, reported in ref. 20. The squared correlation coefficient, R2, is 0.997 and the slope is 1.04 (±0.03) kcal−1.
