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sODF induces OCL formation from C7 cells. (A) The number of TRAP-positive multinucleated cells induced by sODF. C7 cells were cultured in the presence of 10 ng/ml of M-CSF and various concentrations of sODF for 6 days. Data are expressed as means of two cultures. (B) Morphology of OCLs induced from C7 cells in the presence of 20 ng/ml of M-CSF and 0 or 100 ng/ml of sODF. [Bar = 200 μm.]
