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Specific activity of nSMase in different tissues from aSMase-deficient mice (aSMase−/−)
| Tissue | Specific activity, nmol sphingomyelin/mg protein/h |
|---|---|
| Intestine | 113 ± 27 |
| Kidney | 1.6 ± 0.1 |
| Spleen | 1.5 ± 0.2 |
| Heart | 4.8 ± 0.1 |
| Lung | 1.2 ± 0.1 |
| Brain | 582 ± 98 |
| Liver | 2.0 ± 0.5 |
aSMase−/− mice were used to avoid contamination of the enzyme assay by aSMase activity. Results represent mean values (±SD) derived from three independent measurements.
