Table 2.
Procedural and histopathology variables for the ultrasound-guided 8-gauge Mammotome® biopsy technique: For all cases (n = 304), for cases in which an attempt to completely excise the breast lesion was made (n = 235), and for cases in which only diagnostic tissue sampling of the breast lesion was undertaken (n = 69)
| All cases (n = 304) |
Attempted lesion excision (n = 235) |
Only diagnostic lesion sampling (n = 69) |
P-value | |
| Estimated number of Mammotome® cores removed | 8 (2–38) |
9 (3–38) |
6 (2–17) |
< 0.001 |
| Estimated volume of Mammotome® cores removed (cubic cm) | 2.18 (0.26–37.13) |
2.50 (0.60–37.13) |
1.38 (0.26–4.38) |
< 0.001 |
| Percentage of estimated volume of Mammotome® cores removed as compared to volume of original ultrasound lesion |
615% (9%–18,086%) |
730% (113%–18,086%) |
222% (9%–2263%) |
< 0.001 |
| Lesion histopathology | < 0.001 | |||
| Fibroadenoma | 126 (41%) |
112 (48%) |
14 (20%) |
|
| Other benign findings | 107 (35%) |
88 (37%) |
19 (28%) |
|
| Benign tumors | 10 (3%) |
7 (3%) |
3 (4%) |
|
| Invasive breast cancer | 47 (16%) |
20 (9%) |
27 (39%) |
|
| DCIS | 4 (1%) |
2 (1%) |
2 (3%) |
|
| ICPC | 2 (1%) |
1 (< 0.5%) |
1 (1%) |
|
| Lymphoma | 3 (1%) |
1 (< 0.5%) |
2 (3%) |
|
| SQBCC | 1 (< 0.5%) |
0 (0%) |
1 (1%) |
|
| Epithelial atypia | 4 (1%) |
4 (2%) |
0 (0%) |
|
| Post-procedural complications (hematoma formation, skin ecchymosis, or both) | 24 (8%) |
20 (9%) |
4 (6%) |
0.462 |
DCIS, ductal carcinoma in situ; ICPC, intracystic papillary carcinoma; SQBCC, subcutaneous basal cell carcinoma