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. Author manuscript; available in PMC: 2007 Sep 20.
Published in final edited form as: Invest Ophthalmol Vis Sci. 2004 Jan;45(1):48–58. doi: 10.1167/iovs.03-0774

Figure 4.

Figure 4

Photoreceptor deficits in retinas infected with RCAS-En-NeuroDΔC. (A, B) Cells expressing visinin in E9 retinas infected with RCAS-En-NeuroDΔC. (C, D) Cells expressing visinin in E12 retinas infected with RCAS-En-NeuroDΔC. (E) An E7 retina with its peripheral region infected with RCAS-En-NeuroDΔC. Photoreceptor cells are marked by visinin expression (in situ staining, dark stain). Viral infection is revealed by anti-p27 immunohistochemistry (red). (F) Visinin+ cells in an E12 retina infected with RCAS-En. (G) Anti-p27 immunofluorescent staining of the section in (F). Fluorescent signals in the ONL were quenched by the nonfluorescent, Visinin+ signals. (H) Double-labeling for visinin mRNA (dark stain) and p27 (red) of an E15 retina infected with RCAS-En-cNSCL1. Arrows: places where there was a total absence of visinin+ cells. Arrowheads: regions where fewer visinin+ cells were present. Magnification: ×50.