Table 1.
Number of breaks in the ONL of Chick Retinas Infected with RCAS Expressing Various En Constructs
Construct | Breaks (n) | Sections (n) | Breaks per Section (n) | Embryos* (n) | Viral Infection (%) | Breaks per Section† (n) |
---|---|---|---|---|---|---|
En-NeuroDΔC | 996 | 55 | 18.11 | 9 | 20 | 90.55 |
En | 1 | 44 | 0.02 | 6 | 60 | 0.03 |
En-cNSCL1 | 11 | 22 | 0.50 | 3 | 70 | 0.71 |
En-cNSCL2 | 2 | 48 | 0.04 | 6 | 80 | 0.05 |
Data were collected from E9–E18 chick embryos with the virus microinjected into the subretinal space at E2. Retinal cross sections were cut through or adjacent to the meridional plane.
Number of embryos, each with 5 to 8 retinal cross sections counted. Viral infection was the percentage of retinal cells staining positive for p27 and is shown as the average of n retinas.
Normalized for 100% viral infection.