Figure 5. Correlation of Effective Communication Distances with Physical Distances.

(A) Comparison of efficient communication distances (ordinate) and physical distances (abscissa) for all residue pairs in phospholipase A2. The points colored red refer to pairs involving the catalytic residue His48. (B) and (C) illustrate the differences in communication times, for residue pairs separated by similar distances, and the opposite situation of comparable communication times despite significant differences in inter-residue distances, (D) and (E). See text for more details.