Figure 2.
Decreased growth of inoculated tumor metastases, in Cd39-null mice. a: Representative examples of wild-type (right) and Cd39-null (left) mouse lungs at 15 days after tumor cell injection intravenously. b: Wild-type (□) and Cd39-null (▪) lung weights 15 days after intravenous tumor injection. a and b: Mice were injected with 1.5 × 105 B16-F10 cells per 25 g of body weight into the inferior vena cava and lungs were examined at 15 days. Bars represent mean weight ± SEM. *P < 0.006. c: Retention of cell-associated luciferase activity in wild-type (□) and Cd39-null (▪) mice 1 hour after injection of 5 × 105 luciferase-expressing B16-F10 cells (lucB16/F10). Bars represent relative light units (RLUs) per μg of lung ± SD.