Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
COS-1 cells were transfected with NAT2*411T (top) or NAT2*4 (bottom) 24 h before treatment with 5 μM MG-132 (open circles), 5 μM lactacystin (LAC, solid circles), or DMSO as a negative vehicle control (open squares). Cells were harvested at different time points after the treatment, and the cell lysates were tested for SMZ NAT2 catalytic activity. Each data point represents the mean ± standard error of three independent treatments.
