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. Author manuscript; available in PMC: 2007 Sep 21.
Published in final edited form as: Pharmacogenet Genomics. 2007 Jan;17(1):37–45. doi: 10.1097/01.fpc.0000236325.73186.2c

Figure 7.

Figure 7

Top: Multiple alignment of homologous N-acetyltransferases by ClustalW. This picture only shows a partial set of N-acetyltransferase sequences. Dark blue: amino acids identical among species; Light blue: amino acids somewhat similar among species; Yellow: putative catalytic triad: Cys68, His107 and Asn122 (numbered with human NAT2); Green: Leu137, which is conserved among all NATs listed. Bottom: Position of Leu137 (shown by arrow) on the human NAT2 model described in text. The picture is generated by Accelrys Discover Studio ViewPro.