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. Author manuscript; available in PMC: 2008 Aug 1.
Published in final edited form as: Free Radic Biol Med. 2007 Apr 1;43(3):319–331. doi: 10.1016/j.freeradbiomed.2007.03.028

Table 2.

Regulation of Nox and Duox Expression by Agonists and Other Stimuli.

Inducer Nox/Duox Tissues or cells References
Angiotensin II Nox1, Nox4 r-Aortic vascular smooth muscle cells [131]
Urokinase plasminogen activator Nox1, Nox4 r-Aortic vascular smooth muscle cells [132]
Platelet-derived growth factor Nox1 r-Aortic vascular smooth muscle cells [133] (7)
Bone morphologenic protein 4 Nox1 m-Aortic endothelial cells [134]
Prostaglandin F2α Nox1 r-Aortic vascular smooth muscle cells [135]
Phorbol ester Nox1 r-Aortic vascular smooth muscle cells [133]
K-Ras G12V Nox1 r-, m-fibroblast cell line [136]
Vitamin D3 Nox1 h-Colon caner cell line [114]
Interferon-γ Nox1 h-Colon caner cell line [113, 114]
Flagellin (S. enteritidis) Nox1 h-Colon caner cell line [137]
Lipopolysaccharide (H. pylori) Nox1 gp-Gastric mucosal cells [138]
Hypoxia Nox1 h-Pulmonary epithelial cell line [139]
Lipopolysaccharide (E. coli) Nox2 h-Macrophage, h-Granulocyte [140]
IFN-γ; TNF-γ; GM-CSF Nox2 h-Macrophage, h-Granulocyte [140]
M-CSF Nox2 h-Macrophage [140]
TGF-β1 Nox4 h-Cardiac fibroblast cells [141]
TNFα Nox4 h-Aortic vascular smooth muscle cells [142]
Low pH Nox5-short h-Barret esophagus adenocarcinoma
Th-2 cytokines (IL-4, IL-13) Duox1 h-Tracheobronchial epithelial cells [130]
Th-1 cytolikes (IFN-γ, IL-1) Duox2 h-Tracheobronchial epithelial cells [130]

The abbreviations used are: h, human; r, rat; m, mouse, gp, guinea pig.