Table 2.
Inducer | Nox/Duox | Tissues or cells | References |
---|---|---|---|
Angiotensin II | Nox1, Nox4 | r-Aortic vascular smooth muscle cells | [131] |
Urokinase plasminogen activator | Nox1, Nox4 | r-Aortic vascular smooth muscle cells | [132] |
Platelet-derived growth factor | Nox1 | r-Aortic vascular smooth muscle cells | [133] (7) |
Bone morphologenic protein 4 | Nox1 | m-Aortic endothelial cells | [134] |
Prostaglandin F2α | Nox1 | r-Aortic vascular smooth muscle cells | [135] |
Phorbol ester | Nox1 | r-Aortic vascular smooth muscle cells | [133] |
K-Ras G12V | Nox1 | r-, m-fibroblast cell line | [136] |
Vitamin D3 | Nox1 | h-Colon caner cell line | [114] |
Interferon-γ | Nox1 | h-Colon caner cell line | [113, 114] |
Flagellin (S. enteritidis) | Nox1 | h-Colon caner cell line | [137] |
Lipopolysaccharide (H. pylori) | Nox1 | gp-Gastric mucosal cells | [138] |
Hypoxia | Nox1 | h-Pulmonary epithelial cell line | [139] |
Lipopolysaccharide (E. coli) | Nox2 | h-Macrophage, h-Granulocyte | [140] |
IFN-γ; TNF-γ; GM-CSF | Nox2 | h-Macrophage, h-Granulocyte | [140] |
M-CSF | Nox2 | h-Macrophage | [140] |
TGF-β1 | Nox4 | h-Cardiac fibroblast cells | [141] |
TNFα | Nox4 | h-Aortic vascular smooth muscle cells | [142] |
Low pH | Nox5-short | h-Barret esophagus adenocarcinoma | |
Th-2 cytokines (IL-4, IL-13) | Duox1 | h-Tracheobronchial epithelial cells | [130] |
Th-1 cytolikes (IFN-γ, IL-1) | Duox2 | h-Tracheobronchial epithelial cells | [130] |
The abbreviations used are: h, human; r, rat; m, mouse, gp, guinea pig.