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. 2007 Oct 15;93(8):2852–2860. doi: 10.1529/biophysj.107.109819

TABLE 2.

Statistics for the Fn/peptide system

qN% Tip F (pN)
q0.6% Bare 21.4 (6.2)
Peptide 22.5 (9.8)
q2.0% Bare 34.4 (10.2)
Peptide 54.8 (22.3)
q3.0% Bare 55.7 (24.2)
Peptide n.a.

When adsorbed Fn is present, there is a high probability that an interaction with the peptide-functionalized tip will occur. The method used to calculate interactions does not consider the point of separation as an interaction. For both the bare tip and the collagen-related-peptide-functionalized tip, the force increases with surface concentration of Fn. The highest surface concentration used with the collagen-related-peptide-functionalized tip resulted in significant tip fouling, and an interaction force was not calculated. The values were calculated from the empirical probability density function, where μ = Σxipi and σ2 = Σ(xiμ)2pi. Standard deviations are in parentheses. n.a., not applicable.