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. 1998 Mar 31;95(7):3708–3713. doi: 10.1073/pnas.95.7.3708

Figure 3.

Figure 3

Evolution of the novel anti-pathogen toxicity and arginine changes in ECP. Each circle represents one arginine residue in ECP or EDN sequences (see Fig. 2). For the present-day proteins, only the numbers of arginines for human sequences are presented. The average number of arginines for OW monkeys and hominoids is 18.2 for ECP and 7.6 for EDN. The pI value for each protein is also presented. The numbers of amino acid changes to arginines in the branches a–b and a–c in Fig. 1 are given alongside the arrow signs. The numbers of changes from arginines to other amino acids are given in parentheses. MY, million years.