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. Author manuscript; available in PMC: 2007 Dec 1.
Published in final edited form as: Free Radic Biol Med. 2007 Mar 12;42(11):1632–1650. doi: 10.1016/j.freeradbiomed.2007.02.030

Figure 8. Prevention of Radiation-induced Alopecia.

Figure 8

(A) The flanks of guinea pigs were irradiated to 7 Gy daily for 10 days without (top) or with (bottom) topical Tempol application each day prior to irradiation. Hair density remained significantly greater in the Tempol treated group (see dashed box), and hair recovery was more rapid. (B) Typically patients who undergo whole brain irradiation will experience complete alopecia 4–6 weeks post-treatment. Topical application of Tempol resulted in significant reduction of hair loss in this patient who underwent cranial irradiation. (Adapted with permission from reference # 33)