Table 5.
Genes that were ≥two-fold upregulated in A/J (top part) and C57BL/6 (bottom part, next page) at day 17
| Gene Id | Symbol | Gene name | MMU | cM | Biological process | |
|---|---|---|---|---|---|---|
| X14607 | ◇ | Lcn2 | Lipocalin 2 | 2 | 27 | Transport |
| Z71189 | ◇ | Acadvl | Acyl-Co A dehydrogenase, very long chain | 11 | 38 | Electron transport; fatty acid metabolism |
| X03766 | ◇ | Acta1 | Actin, alpha 1, skeletal muscle | Muscle contraction; cytoskeleton org and biogenesis | ||
| NM_009171 | ◇ | Shmt1 | Serine hydroxymethyl transferase 1 | 11 | 77 | One-carbon compound; amino-acid metabolism |
| L02331 | ◇ | Sult1a1 | Sulphotransferase family 1A | 7 | 4 | Steroid metabolism |
| NM_011868 | ◇ | Peci | Peroxisomal Δ3, Δ2-enoyl-CoA isomerase | 13 | 60 | Metabolism; peroxisome organization and biogenesis |
| NM_010763 | ◇ | Man1b | Mannosidase 1, beta | 3 | 110 | Carbohydrate metabolism; N-linked glycosylation |
| AF218416 | ◇ | Ttpa | Tocopherol (alpha) transfer protein | 4 | 82.5 | Transport; embryo implantation; vitamin E metabolism |
| NM_019573 | ◇ | Wwox | WW domain-containing oxidoreductase | 8 | 72.4 | Metabolism; induction of apoptosis |
| NM_011044 | ◇ | Pck1 | Phosphoenolpyruvate carboxykinase 1 | 2 | 103 | Gluconeogenesis |
| NM_018829 | ◇ | Ap3m1 | Adaptor-related protein complex 3 | 14 | 2.5 | Intracell protein transport; protein-lysosome targeting |
| NM_009286 | ◇ | Sth2 | Sulphotransferase, hydroxysteroid pref 2 | Steroid metabolism | ||
| NM_008489 | ◇ | Lbp | Lipopolysaccharide binding protein | 2 | 83 | Xenobiotic metabolism; lipid transport |
| NM_008768 | ◇∞ | Orm1 | Orosomucoid 1 | 4 | 31.4 | Transport; acute-phase response |
| U89889 | ◇∞ | Hpxn | Hemopexin | 7 | 74.5 | Transport; acute-phase response |
| NM_019577 | ∞ | Ccl24 | Chemokine (C-C motif) ligand 24 | 5 | 83 | Chemotaxis; inflammatory response; immune response |
| NM_018866 | ∞ | Cxcl13 | Chemokine (C-X-C motif) ligand 13 | 5 | 83 | Chemotaxis; inflammatory response; immune response |
| NM_010392 | ∞ | H2-Q2 | Histocompatibility 2, Q region locus 8 | -1 | Defense response | |
| NM_011338 | ∞ | Ccl9 | Chemokine (C-C motif) ligand 9 | 11 | 47.4 | Signal transduction; chemotaxis; immune response |
| NM_007827 | ∞ | Daf2 | Decay accelerating factor 2 | 1 | 67.6 | Complement activation, classical pathway |
| NM_011316 | ∞ | Saa4 | Serum amyloid A 4 | 7 | 23.5 | Acute-phase response |
| NM_021443 | ∞ | Ccl8 | Chemokine (C-C motif) ligand 8 | 11 | 47 | Signal transduc; chemotaxis; inflamm; immune response |
| NM_010740 | ∞ | C1qr1 | Complement component 1 q receptor 1 | 2 | 84 | Cell adhesion; defense response |
| NM_007643 | ∞ | Cd36 | CD36 antigen | 5 | 2 | Cell adhesion; transport |
| NM_011579 | ∞ | Tgtp | T-cell-specific GTPase | 11 | 77 | |
| NM_010766 | ∞ | Marco | Macrophage receptor/collagenous struct | |||
| NM_009921 | ∞ | Camp | Cathelicidin antimicrobial peptide | 9 | 61 | Xenobiotic metabolism; defense response |
| M83218 | ∞ | S100a8 | S100 calcium binding protein A8 | 3 | 43.6 | Chemotaxis |
| NM_019948 | ∞ | Clecsf9 | C-type lectin, superfamily member 9 | 6 | 59.6 | |
| K02782 | ∞ | C3 | Complement component 3 | 17 | 34.3 | Inflammatory response; complement activation |
| NM_017370 | ∞∴ | Hp | Haptoglobin | 8 | 55 | Acute-phase response; proteolysis and peptidolysis |
| NM_010517 | ∞& | Igfbp4 | Insulin-like growth factor bindg prot | 11 | 77 | Regulation of cell growth |
| NM_008176 | ∞& | Cxcl1 | Chemokine (C-X-C motif) ligand 1 | 5 | 51 | Cell growth/maintenance; inflamm; immune response |
| NM_009984 | ∴ | Ctsl | Cathepsin L | 13 | 30 | Proteolysis and peptidolysis |
| NM_021445 | ∴ | Cts6 | Cathepsin 6 | 13 | 35.5 | Proteolysis and peptidolysis |
| NM_019447 | ∴ | Hgfac | Hepatocyte growth factor activator | 5 | 83 | Proteolysis and peptidolysis |
| NM_020269 | ‡ | Kcnj10 | K inwardly-rectifying channel, subfam J | 1 | 93.5 | Ion transport; potassium ion transport |
| AF020711 | ‡ | Kcnmb1 | K large conductance Ca-activ channel | 11 | 77 | Potassium ion transport |
| NM_019659 | ‡ | Kcnj1 | K inwardly-rectifying channel, subfam J | 9 | 78.8 | Ion transport; potassium ion transport |
| NM_007502 | ‡ | Atp1b3 | ATPase, Na+/K+ trans, beta 3 polypeptide | 9 | 51 | Potassium ion transport; sodium ion transport |
| NM_010656 | & | Sspn | Sarcospan | 6 | 71.55 | Cell growth/maintenance; regulation of cell cycle |
| NM_011318 | Apcs | Serum amyloid P-component | 1 | 94.2 | ||
| NM_010508 | Ifnar1 | Interferon (alpha and beta) receptor 2 | 16 | 63.2 | ||
| NM_007598 | Cap1 | Adenylyl cyclase-assoc CAP prot homologue | 4 | 82.5 | Cellular morphogenesis | |
| NM_021304 | Abhd1 | Abhydrolase domain containing 1 | 5 | 83 | Biological_process unknown | |
| NM_011314 | Saa2 | Serum amyloid A 2 | 7 | 23.5 | Acute-phase response | |
| NM_011336 | Ccl27 | Chemokine (C-C motif) ligand 27 | Immune response | |||
| NM_007846 | Defcrs12 | Defensin-related sequence 7 | ||||
| NM_018858 | Pbp | Phosphatidylethanolamine binding protein | 5 | 63 | ||
| NM_007752 | Cp | Ceruloplasmin | 3 | 55 | ||
| NM_009221 | Snca | Synuclein, alpha | 6 | 29 | ||
| AB018421 | Cyp4a10 | Cytochrome P450, family 4 | 4 | 49.5 | ||
| NM_010442 | Hmox1 | Heme oxygenase (decycling) 1 | 8 | 35 | Heme oxidation | |
| NM_007822 | Cyp4a14 | Cytochrome P450, family 4 | 4 | 49.5 | Electron transport | |
| NM_018777 | Cldn6 | Claudin 6 | 17 | 71.3 | ||
| AF290877 | Wasf1 | WASP family 1 | 10 | 25 | Cell motility; protein complex assembly; cell morphogen | |
| NM_021398 | pending | Embryonic epithelial gene 1 | 2 | 106.6 | ||
| NM_016974 | Dbp | D site albumin promoter binding protein | 7 | 23 | Circadian rhythm; regulation of transcription | |
| NM_010091 | Dvl1 | Dishevelled, dsh homolog 1 (Drosophila) | 4 | 82 | Development; Wnt receptor signalling pathway | |
| NM_011620 | Tnnt3 | Troponin T3, skeletal, fast | 7 | 69 | Regulation of muscle contraction; muscle development | |
| NM_007468 | Apoa4 | Apolipoprotein A-IV | 9 | 27 | Lipid transport; regulation of cholesterol absorption | |
| NM_015779 | ||||||
| NM_009376 | TgN737Rpw | Transgene inser737,polycystic kidney dis | 14 | 21 | Ant/post pattern formation; digit morphogenesis | |
| NM_009747 | Bdkrb2 | Bradykinin receptor, beta 2 | 12 | 53 | G-protein coupled receptor protein signalling pathway | |
| NM_013933 | Vapa | Vesicle-associated membrane protein | 17 | 71.3 | Biological_process unknown; cell motility | |
| NM_019744 | Ncoa4 | Nuclear receptor coactivator 4 | 14 | 75 | Biological_process unknown | |
| NM_009114 | S100a9 | S100 calcium binding protein A9 | 3 | 43.6 | ||
| NM_009175 | Siat1 | Sialyltransferase 1 | 16 | 15.5 | Protein amino-acid glycosylation | |
| NM_007411 | Adk | Adenosine kinase | 14 | 75 | Purine salvage | |
| NM_013532 | Gp49b | Glycoprotein 49 B | 10 | 32 | ||
| M27608 | Mup1 | Major urinary protein 1 | Transport; immediate hypersensitivity response | |||
| NM_009688 | Birc4 | Baculoviral IAP repeat-containing 4 | X | 55 | Apoptosis; antiapoptosis | |
| NM_008648 | Mup4 | Major urinary protein 4 | 4 | 27.8 | Transport | |
| NM_010406 | Hc | Haemolytic complement | 2 | 23.5 | Cytolysis; inflammatory response; complement activation | |
| NM_011183 | Psen2 | Presenilin 2 | Intracellular signalling cascade | |||
| D00232 | ||||||
| L11333 | Es31 | Esterase 31 | 8 | |||
| NM_011341 | Sdf4 | Stromal cell-derived factor 4 | 4 | 82.5 | ||
| NM_007546 | Biklk | Bcl2-interacting killer-like | 15 | 64 | ||
| NM_021537 | Stk25 | Serine/threonine kinase 25 (yeast) | 1 | 58 | Protein phosphorylation | |
| NM_013653 | Ccl5 | Chemokine (C-C motif) ligand 5 | 11 | 47.4 | Signal transduc; chemotaxis; inflamm; immune response | |
| AF221095 | Ndst3 | N-deacetylase/N-sulphotransferase | 3 | 110 | ||
| AF246218 | Shkbp1 | Sh3kbp1 binding protein 1 | 7 | 74.5 | Biological_process unknown | |
| NM_010924 | Nnmt | Nicotinamide N-methyltransferase | 9 | 29 | ||
| NM_007606 | Car3 | Carbonic anhydrase 3 | 3 | 11.7 | One-carbon compound metabolism | |
| NM_008182 | Gsta2 | Glutathione S-transferase, alpha 2 (Yc2) | 9 | 44 | ||
| NM_019414 | Selenbp2 | Selenium binding protein 2 | 3 | 50.8 | ||
| AJ290944 | Usmg2 | Upreg during skeletal muscle growth | ||||
| M83538 | ||||||
| AF022856 | Nrp2 | Neuropilin 2 | Cell adhesion | |||
| NM_007925 | Eln | Elastin | 5 | 75 |