HindIII map of CPV (18) with locations of crmB, crmC, and crmD and cognate crmD regions in ECT, VAR, camelpox Somalia, monkeypox Copenhagen, and VAC DNAs [arrow = transcription direction; B22R and G1R reading frames flank the crmD region, which is absent in VAR DNA (13, 14) and DNA of CML, MPV, and VAC as indicated].