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. 2001 Feb 1;107(3):325–331. doi: 10.1172/JCI6749

Figure 2.

Figure 2

Nociceptive responses in EP1 receptor–deficient mice. (a) Acetic acid–induced stretching. The number of stretches was counted for 20 minutes immediately after 0.7% acetic acid injection intraperitoneally. Piroxicam (5 mg/kg subcutaneously) or vehicle was administered 30 minutes before acetic acid treatment. n = 8 for each group. AP < 0.01. (b) PBQ-induced stretching. Stretching behaviors were induced by injection of 0.02% PBQ intraperitoneally. The number of stretches was counted from 5 to 15 minutes after PBQ treatment. n = 9 EP1+/– (filled bar) and n = 11 EP1–/– (open bar) mice. AP < 0.05.

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