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Weight curve of male MCH-transgenic heterozygotes on high-fat diet (a) shows no significant increase in body weight of MCH heterozygotes (P = NS, repeated measures ANOVA). Male MCH-transgenic homozygotes on standard diet (b) show no significant increase (P = NS, repeated measures ANOVA) in body weight. Male MCH-transgenic homozygotes on a high-fat diet (c) show a significant increase (P < 0.001, repeated measures ANOVA) in body weight.
