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Prolonged survival of islet allografts induced by anti-CD45RB mAb MB23G2. Kaplan–Meier plot of cumulative allograft survival vs. time. Treatment groups: ▴, untreated controls (n = 5); □, anti-CD45RB administered to recipient animals on days −1, 0, and 5 (n = 14, P = 0.002 vs. control); ○, anti-CD45RB administered to the donor animals on days −5, −1, and 0 (n = 4, P = NS vs. control).
