Table 4.
Ranks assigned to approaches used in normalizing blocks of replicates containing relative peptide abundances in the presence of biological variability. Ranks were assigned on the percent reduction in the pooled estimate of variability (PEV) and median coefficient of variability (CV). The lower the value of the rank the greater the percent reduction. Values in parentheses represent the standard deviation of ranks
| Pooled Estimate of Variance (PEV) | ||||||||
|---|---|---|---|---|---|---|---|---|
| Early-log versus Stationary | Stressed versus Controlled Tissue | |||||||
| Block | CT | LinReg | LocReg | Quan | CT | LinReg | LocReg | Quan |
| 1 | 3 | 1 | 2 | 4 | 3 | 2 | 4 | 1 |
| 2 | 3 | 2 | 4 | 1 | 2 | 3 | 4 | 1 |
| 3 | 2 | 3 | 4 | 1 | 3 | 2 | 4 | 1 |
| 4 | 2 | 3 | 4 | 1 | 3 | 2 | 4 | 1 |
| Mean | 2.5 (±0.5) | 2.25 (± 0.9) | 3.5 (±1.0) | 1.75 (±1.5) | 2.75 (±0.5) | 2.25 (±0.5) | 4.0 (±0.0) | 1.0 (±0.0) |
| Median Coefficient of Variation (CV) | ||||||||
| Early-log vs Stationary | Meth vs Norm | |||||||
| Block | CT | LinReg | LocReg | Quan | CT | LinReg | LocReg | Quan |
| 1 | 3 | 2 | 4 | 1 | 1 | 2 | 4 | 3 |
| 2 | 1 | 2 | 3 | 4 | 2 | 3 | 4 | 1 |
| 3 | 1 | 2 | 3 | 4 | 1 | 2 | 4 | 3 |
| 4 | 1 | 2 | 3 | 4 | 1 | 2 | 4 | 3 |
| Mean | 1.5 (±1.0) | 2.0 (±0.0) | 3.25 (±0.5) | 3.25 (±1.5) | 1.25 (±0.5) | 2.25 (±0.5) | 4.0 (±0.0) | 2.5 (±1.0) |