Table 1.
Production of C-C chemokines in activated cells from HEH
| A | HEH, pg/ml culture
|
|||
|---|---|---|---|---|
| MIP-1α | MIP-1β | RANTES | 3H-T | |
| Mean | 33,100 | 31,900 | 39,000 | 17,200 |
| Median | 30,300 | 23,100 | 42,800 | 16,300 |
| n | 14 | 14 | 14 | 14 |
| Seronegative controls | ||||
| Mean | 15,000 | 16,500 | 24,700 | 19,000 |
| Median | 11,400 | 14,200 | 19,000 | 17,500 |
| n | 14 | 14 | 14 | 14 |
| Student’s t test | t = 2.975 | t = 2.430 | t = 2.210 | Not significant |
| P < 0.01 | P < 0.05 | P < 0.05 | ||
| B | HEH
|
Seronegative controls
|
|||
|---|---|---|---|---|---|
| MIP-1α | MIP-1β | MIP-1α | MIP-1β | ||
| Mean | 38,800 | 41,300 | 16,800 | 16,600 | |
| Median | 39,800 | 39,100 | 15,900 | 14,800 | |
| n | 8 | 8 | 8 | 8 | |
| Unexposed mild hemophiliacs
|
Unexposed severe hemophiliacs
|
||||
|---|---|---|---|---|---|
| MIP-1α | MIP-1β | MIP-1α | MIP-1β | ||
| Mean | 18,300 | 12,000 | 16,900 | 16,300 | |
| Median | 17,900 | 10,500 | 16,900 | 9,400 | |
| n | 8 | 8 | 8 | 8 | |