Fig. 5.
Neuronophagia by infiltrative microglial/macrophages (small arrows) of dopaminergic neurons that have undergone vacuolar degeneration (large arrows) in the SN/VTA region of a 4-week-old PKU mouse. Note shredding and vacuolation of surrounding neuropil. Tyrosine hydroxylase immunoperoxidase method; scale bar=10 μm.