Figure 2.
Longitudinal studies of progenitor cells from three representative female Safari cats. In cat 63848, a slow change toward a dominance of progenitor cells with a G G6PD phenotype was seen. Significant deviation from the mean value was first observed at age 8.4 years, when the data are analyzed by sequential χ2 analyses. In cat 65044, a significant change in the percent of progenitors with d G6PD was first noted at age 6.3 years, and a change in the phenotype of cells from cat 40631 was evident by year 2.7. Although a similar drift occurred among red cells and granulocytes (data not shown), the G6PD phenotype of T cells remained unchanged and specifically was 60% (year 13) in cat 63848, 60% (year 12) in cat 65044, and 60% (year 7) in cat 40631.