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. 1998 Mar 31;95(7):3862–3866. doi: 10.1073/pnas.95.7.3862

Table 1.

Autologous marrow transplantation (AMT) studies in elderly female Safari cats

Cat Age, years Time after AMT, months % of cells with d G6PD
Progenitors Granulocytes T cells Marrow fibroblasts
65044 3 60 50 50 60
12 7 15 60 50
3 7 10 10 50
15 3 10 5 50
41008 5 7 7 45 55
3 10 10 10 50
20 13 10 10 50

Longitudinal data from cat 65044 are presented in Fig. 2. Cat 41008, used in breeding studies of F2 animals, did not have the G6PD phenotype of her progenitors measured until age 5 years. Values remained unchanged in four determinations over 9 months before transplantation and the percent of progenitors with d G6PD ranged from 2 to 7%, granulocytes from 5 to 10%, and T cells from 40 to 50%. After transplantation, the distributin of G6PD phenotype in T cells became equivalent to that among progenitors and granulocytes, and a balanced distribution of G6PD phenotype persisted among marrow fibroblasts, a nonhematopoietic (control) cell population.