Table 2.
Cell surface phenotype of transgenic lymphocytes
| Animal number | Percent of spleen cells positive for
|
WBC*, × 106 | ||
|---|---|---|---|---|
| CD3 | CD4 | CD8 | ||
| N 1 | 36.0 | 21.0 | 12.0 | 1.8 |
| N 2 | 35.0 | 24.0 | 12.0 | 1.8 |
| N 3 | 36.0 | 22.0 | 16.0 | ND |
| TG 37 | 63.0 | 17.0 | 29.0 | 2.6 |
| TG 54 | 57.0 | 21.0 | 34.0 | 6.2 |
| TG 60 | 54.0 | 33.0 | 17.0 | 11.6 |
| TG 68 | 55.0 | 34.0 | 21.0 | ND |
| TG 72 | 64.0 | 37.0 | 22.0 | ND |
| TG 73 | 67.0 | 31.0 | 27.0 | 5.6 |
| TG 74 | 70.0 | 32.0 | 30.0 | 2.4 |
| TG 83 | 49.0 | 23.0 | 30.0 | ND |
| TG 108 | 65.0 | 27.0 | 24.0 | 2.4 |
| TG 109 | 63.0 | 22.0 | 35.0 | 1.8 |
| TG 116 | 52.0 | 27.0 | 26.0 | 24.8 |
| TG 117 | 55.0 | 24.0 | 22.0 | ND |
| TL 25 | 65.0 | 1.0 | 60.0 | ND |
| TL 39 | 99.0 | 1.4 | 97.0 | 168.0 |
| TL 47 | 65.0 | 20.0 | 40.0 | ND |
| TL 53 | 75.0 | 3.0 | 74.0 | ND |
| TL 71 | 63.0 | 21.0 | 40.0 | ND |
| TL 82 | 65.0 | 10.0 | 73.0 | ND |
N, normal; TG, transgenic; TL, T cell leukemic mice; ND, not done.
*
The mean WBC/ml blood for normal adult mice (10–18 months old) was 2.6 ± 0.4 × 106 cells/ml (n = 10).