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. 1998 Mar 31;95(7):3902–3907. doi: 10.1073/pnas.95.7.3902

Figure 2.

Figure 2

Long-term growth capacity of α6bri and α6dim cells. (A) Growth curves of UF cells and the α6bri and α6dim fractions in a representative experiment are shown. Each point represents the mean cell output ± SEM of three replicate wells obtained at each passage. The curves show that the α6bri cells consistently grew at a greater rate than the UF cells and the α6dim fraction. (Inset) Growth curves from day 0–50 to illustrate cell proliferation during this period, which is not evident on the main graph due to the scale. These results are typical of several replicate experiments (n = 5). (B) The total cell output (cumulative cell yield) from 5,000 cells of each fraction was determined at the end of the experiment when their ability to proliferate was exhausted. The total cell output of the α6bri fraction was significantly higher than the α6dim fraction and UF cells (P < 0.05), thus confirming that the α6bri population had the greatest long-term proliferative capacity. The numbers above the columns indicate mean cell yields from each fraction. The results shown represent the mean total output ± SEM of three separate experiments.