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. Author manuscript; available in PMC: 2007 Sep 24.
Published in final edited form as: Biochemistry. 2005 Feb 22;44(7):2632–2641. doi: 10.1021/bi0477900

Figure 2. Effect of CYP2B4 and CYP1A2 mediated PROD metabolism as a function of divalent cation concentration.

Figure 2

Experimental conditions are the same as figure 1 with the exception of buffer medium. Varying amounts of the divalent cation magnesium chloride in 50 mM HEPES buffer was used to test the effects of ionic strength on P450 metabolism in the binary and ternary systems shown.