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. Author manuscript; available in PMC: 2007 Sep 24.
Published in final edited form as: Biochemistry. 2005 Feb 22;44(7):2632–2641. doi: 10.1021/bi0477900

Figure 3. Effect of CYP2B4 and CYP1A2 mediated 7-EFC metabolism as a function of ionic strength.

Figure 3

CYP2B4, CYP1A2 and reductase were reconstituted in binary (one P450) and ternary (mixed P450s) reconstituted systems. Experimental conditions are described in materials and methods and figure 1. Each group represents the mean ± SEM for three determinations. Significant differences in activities between the sum of the two binary systems compared to the mixed reconstituted system are indicated (*, p < 0.05; **, p < 0.01; ***, p < 0.001).