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Conversion of 12-Halododecanoic Acids by CYP52A21
| Substrates | 12-hydroxydodecanoic
acid |
12-oxododecanoic
acid |
11-hydroxydodecanoic
acid |
Total conversion | ω/(ω-1) |
|---|---|---|---|---|---|
| % | |||||
| 12-chlorododecanoic
acid |
1.5 ± 0.4 | 4.2 ± 0.2 | 5.7 ± 0.2 | 0.36 ± 0.27 | |
| 12-bromododecanoic
acid |
1.5 ± 0.1 | 1.1 ± 0.1 | 2.6 ± 0.1 | 1.36 ± 0.11 | |
| 12-iodododecanoic
acid |
1.1 ± 0.2 | < 0.1 | 1.1 ± 0.2 | ||
